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Serum antibody concentration and affinity
A new type of quantitative serum-antibody profiling: When studying the immune response to a drug, a vaccine, or an antigen, established serological technologies, such as ELISA, only provide semi-quantitative outputs such as titer.
Affinity and stoichiometry to amyloid species
Protein aggregates in neurodegenerative diseases: Protein aggregates are clusters of misfolded proteins in the form of oligomers, tangles, plaques, and fibrils. A wide range of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’...
Binding of Fc-engineered IgC antibodies to FcRn
The making of therapeutic antibodies: Antibodies represent one of the most prevalent therapeutic approaches, with a wide range of variations available to optimize function across oncology, neurology, and immunology. The successful transition from de...
Fluidity One-M
Quantify binding affinity, size, concentration and stoichiometry in solution, all at once. Proteins play criticalroles in the human body, maintaining and regulating the structure and function of tissues and organs.
  • Videos
Microfluidic Diffusional Sizing (MDS)
A new class of in-solution protein interaction measurement. MDS gives one simple and direct measurement – protein molecular size. When binding occurs, changes in protein size are monitored and used to determine binding affinity and calibration-free...
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  • Autoimmune disease
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  • Tools
Binding curve simulator
This simulator will draw the binding curve over a selected concentration range of titrated species given the selected affinity (KD) and probe concentration. The curve is scaled to hydrodynamic radius (Rh), transitioning from purely unbound probe to c...
Labeling Calculator
Check out our Labeling Calculator, a tool that helps with volume and concentration calculations when labeling proteins required for MDS assays. This calculator is designed to work with our NHS ester labeling guide which provides detailed guidance on ...
Fluidic Sciences Ltd