News and Blogs

Protein-protein interactions (PPIs) are fundamental to biological processes, and understanding these interactions is crucial for drug discovery, disease research, and molecular biology [1]. A truly effective PPI binding assay should be highly...

The fuzziness of intrinsically disordered proteins Protein–protein interactions (PPIs) are fundamental to all cellular functions. The mechanism by which we understand these interactions has evolved from the early “lock and key” model [1] to the...

In this blog post we delve into the definition of GPCRs, reasons behind why elucidating GPCR structures are so important as well as why they are hard to study. Why are GPCRs important? G protein-coupled receptors (GPCRs) make up the largest family...

The stoichiometry, or relative number, of proteins in a complex is one of those aspects of bioscience that is often hard to infer or quantify. However, it is increasingly seen as more and more important in drug discovery and disease pathology. The...